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The kidney is a major source of the plasma enzyme glutathione peroxidase. We measured plasma glutathione peroxidase activity in 130 patients affected with difFerent renal diseases at various stages, and compared it with the following indices of kidney function: serum creatinine, creatinine clearance, and urinary excretion of a 1 -microglobulin, ß 2 -microglobulin, albumin and N-acetyl-ß-D-glucosaminidase. Plasma glutathione peroxidase activity appeared significantly reduced in most of the renaldoi:10.1515/cclm.19220.127.116.119 fatcat:ydsqi2p2kbfllhgxasksfoyvta