Antimicrobial efficiency of Curculigo orchioides callus extract was examined against Escherichia coli, Proteus vulgaris, Salmonella typhimurium, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus and Candida albicans. The zone of inhibitions are determined at 10 mg/ml concentration of methanol extracts of callus on agar well plate and MIC against tested microorganism. The zone of inhibition ranged between 8.7 ± 1.5 (Pseudomonas aeruginosa) and 16.0 ± 1.3 mm (Staphylococcus aureus).

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... he finding's indicate that the callus extract of Curculigo orchioides show better inhibitory activity against only gram positive bacteria such as Staphylococcus aureus, Bacillus cereus than gram negative bacteria such as like Escherichia coli, Salmonella typhimurium , Pseudomonas aeruginosa and Proteus vulgaris. However the methanol extract showed good zone of inhibition with fungi (Candida albicans). Similar results have been observed in the minimum inhibitory concentration assays. The results indicate that Curculigo orchioides callus extract has good antimicrobial activity against the tested organisms because of the presence of phytoconstituents. Further work is needed to isolate the active principle from the plant extracts and to carry out pharmacological studies.