Use of the probability of stone formation (PSF) score to assess stone forming risk and treatment response in a cohort of Brazilian stone formers

Benjamin Turney, William Robertson, Oliver Wiseman, Carmen Regina P. R. Amaro, Victor A. Leitão, Isabela Leme da Silva, João Luiz Amaro
2014 International Brazilian Journal of Urology  
ARTICLE INFO ______________________________________________________________ ______________________ Introduction: The aim was to confirm that PSF (probability of stone formation) changed appropriately following medical therapy on recurrent stone formers. Materials and Methods: Data were collected on 26 Brazilian stone-formers. A baseline 24-hour urine collection was performed prior to treatment. Details of the medical treatment initiated for stone-disease were recorded. A PSF calculation was
more » ... calculation was performed on the 24 hour urine sample using the 7 urinary parameters required: voided volume, oxalate, calcium, urate, pH, citrate and magnesium. A repeat 24-hour urine sample was performed for PSF calculation after treatment. Comparison was made between the PSF scores before and during treatment. Results: At baseline, 20 of the 26 patients (77%) had a high PSF score (> 0.5). Of the 26 patients, 17 (65%) showed an overall reduction in their PSF profiles with a medical treatment regimen. Eleven patients (42%) changed from a high risk (PSF > 0.5) to a low risk (PSF < 0.5) and 6 patients reduced their risk score but did not change risk category. Six (23%) patients remained in a high risk category (> 0.5) during both assessments. Conclusions: The PSF score reduced following medical treatment in the majority of patients in this cohort.
doi:10.1590/s1677-5538.ibju.2014.04.09 pmid:25251955 fatcat:baewmjcxords3he7afcxui3yvu