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A benchmark problem is described for the reconstruction and analysis of biochemical networks given sampled experimental data. The growth of the organisms is described in a bioreactor in which one substrate is fed into the reactor with a given feed rate and feed concentration. Measurements for some intracellular components are provided representing a small biochemical network. Problems of reverse engineering, parameter estimation, and identifiability are addressed. The contribution mainlydoi:10.1101/gr.1226004 pmid:15342560 pmcid:PMC515324 fatcat:ceptheigfvekndnnhyes6lwqeq