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The Cluster-Span Threshold (CST) is a recently introduced unbiased threshold for functional connectivity networks. This binarisation technique offers a natural trade-off of sparsity and density of information by balancing the ratio of closed to open triples in the network topology. Here we present findings comparing it with the Union of Shortest Paths (USP), another recently proposed objective method. We analyse standard network metrics of binarised networks for sensitivity to clinicaldoi:10.1109/embc.2016.7591318 pmid:28268906 dblp:conf/embc/SmithAE16 fatcat:7juadwwf5neuzi42xfpn7mknue