Structural Studies of a Complex Between Endothelial Nitric Oxide Synthase and Calmodulin at Physiological Calcium Concentration

Michael Piazza, Thorsten Dieckmann, J. Guy Guillemette
2016 Biochemistry  
binding domain peptide in complex; PDB, Protein Data Bank; HSQC, heteronuclear single-quantum coherence; apoCaM, Ca 2+ deplete CaM; PELDOR, pulsed electron-electron double resonance; FRET, fluorescence resonance energy transfer; EM, electron cryo-microscopy; SPR, surface plasmon resonance; CaM12, CaM protein defective in Ca 2+ binding in the N-lobe EF hands with CaM D20A and D56A mutations; CaM34, CaM protein defective in Ca 2+ binding in the C-lobe EF hands with CaM D93A and D129A mutations;
more » ... m.s.d., root-mean-square distance; H/D, hydrogen/deuterium.
doi:10.1021/acs.biochem.6b00821 pmid:27696828 fatcat:ej2cqigamnca3pc5eztluxk63a