Percutaneous Transhepatic Cholangioscopy and Palliative Photodynamic Therapy of a Cholangiocellular Carcinoma (Klatskin Tumor)

J Herzog, A Eickhoff
2013 Video Journal and Encyclopedia of GI Endoscopy  
Owing to the growth direction of cholangiocellular carcinomas along the bile ducts, these tumors are often detected in a late stage. Klatskin tumors are mostly presented by jaundice. In cases of advanced inoperable tumors, a palliative photodynamic therapy (PDT) is possible. The aim of a PDT is a selective destruction of tumor tissue caused by the activation of photosensitizers by laser light. After the application of photosensitizers, they accumulate in the tumor and photochemistry reactions
more » ... emistry reactions start by the influence of laser light. This leads to tumor necrosis. A common photosensitizer for cholangiocellular carcinomas is photofrin. After a PDT, it is necessary to perform light protection for nearly 2 months. The authors present a case of a patient who underwent percutaneous transhepatic cholangioscopy and palliative PDT of a cholangiocellular carcinoma (Klatskin tumor). This article is part of an expert video encyclopedia.
doi:10.1016/s2212-0971(13)70225-5 fatcat:6mvi3ypwrjartmbxgigb2pmfsa