Contrast-enhanced ultrasound-guided radiofrequency ablation in inconspicuous hepatocellular carcinoma on B-mode ultrasound

Eui Joo Kim, Yun Soo Kim, Seung Kak Shin, Oh Sang Kwon, Duck Joo Choi, Ju Hyun Kim
<span title="2017-11-07">2017</span> <i title="AVES Publishing Co."> <a target="_blank" rel="noopener" href="" style="color: black;">The Turkish Journal of Gastroenterology</a> </i> &nbsp;
Recently, novel contrast agents for ultrasound have been developed to improve the diagnostic yield. Son-oVue (Bracco, Milan, Italy) and Sonazoid (Daiichi-San-Turk ABSTRACT Background/Aims: B-mode ultrasound (US) has difficulty targeting small hepatocellular carcinomas (HCCs) with poor conspicuity during radiofrequency ablation (RFA). Contrast-enhanced ultrasound (CEUS) can improve visualization of small or inconspicuous HCCs. This study was conducted to evaluate the effectiveness of CEUS-guided
more &raquo; ... RFA electrode insertion during the arterial phase in inconspicuous HCCs. Materials and Methods: Ninety-three treatment-naïve HCCs from 80 patients treated with RFA from August 2012 to December 2014 were retrospectively reviewed. Seventy-five HCCs from 65 patients underwent Bmode US-guided RFA, and 15 HCCs from 14 patients that were inconspicuous on B-mode US underwent CEUS-guided RFA during the arterial phase after injection of sulfur hexafluoride microbubbles (SonoVue®). Technical success was assessed by contrast-enhanced computed tomography within 1 week and 3 months after the procedure. Results: The mean size of HCCs treated with CEUS-guided RFA was smaller than that of HCCs treated with B-mode US-guided RFA (1.17±0.36 vs. 1.63±0.55 cm, p=0.003). Technical success rates of CEUS-guided RFA within 1 week and 3 months were 100% (15/15) and 93.3% (14/15), respectively. Technical success rates of B-mode US-guided RFA were 97.3% (73/75) and 94.5% (69/73), respectively. Conclusion: CEUS-guided RFA is highly efficacious for ablation of very small and inconspicuous HCCs. Cite this article as: Kim EJ, Kim YS, Shin SK, Kwon OS, Choi DJ, Kim JH. Contrast-enhanced ultrasound-guided radiofrequency ablation in inconspicuous hepatocellular carcinoma on B-mode ultrasound. Turk J Gastroenterol 2017; 28: 446-52. Liver Original Article
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="">doi:10.5152/tjg.2017.17104</a> <a target="_blank" rel="external noopener" href="">pmid:29086712</a> <a target="_blank" rel="external noopener" href="">fatcat:dh3idp2jzvaobinhxtsbdaaxwq</a> </span>
<a target="_blank" rel="noopener" href="" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href=""> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / </button> </a>