SP0039 I graduated! education for children and adolescents with rmds

T.C. Wilhelmer
2018 THURSDAY, 14 JUNE 2018   unpublished
Free fatty acids (FFA's) are grouped based on the length of their carbon chains into short chain fatty acids (SCFAs), medium chain fatty acids (MCFAs) and long chain fatty acids (LCFAs). The most FFAs are released after breakdown of triglycerides in adipose tissue and the liver. However, SCFAs including acetate, propionate and butyrate are derived from the fermentation of fibres in the gut. In this presentation, the good or the bad properties of FFA's to control or aggravate inflammation in
more » ... inflammation in general will be discussed. With special focus on rheumatic disorders, such as rheumatoid arthritis and gout. In addition, the synergy of LCFAs with damage associated molecular patterns (DAMPs) will be addressed. Finally, the therapeutic value of SCFAs will be discussed in rheumatic disorders.
doi:10.1136/annrheumdis-2018-eular.7802 fatcat:4l6c2cuml5gz5exapds7dq6ni4