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The transdermal delivery of drugs and, in more general terms, of active principles can be performed by iontophoresis and/or by electroporation. The advantages of a local treatment vs. other drugs intake methods are well known as it reduces the systemic involvement and therefore the systemic contraindications. To perform the treatment exploiting the electroporation effect there is nowadays a specific variant of a known medical device used in physiotherapy: the Medium Frequencydoi:10.23958/ijirms/vol06-i03/1093 fatcat:nh4dlxaekvgzrk6sznbas4eoxa