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Possible activation of murine T lymphocyte through CD98 is independent of interleukin 2/interleukin 2 receptor system
2006
Biomedical research
CD98 is a widely expressed cell surface heterodimetric protein of 125 kDa. Its expression is upregulated during lymphocyte activation induced by mitogen, superantigen, conventional antigen, and a combination of phorbol myristate acetate (PMA) and ionomycin. However, the role of CD98 in the immune system is not so well understood. The role of CD98 in murine T lymphocyte proliferation was investigated, especially in correlation with the interleukin 2 (IL-2)/interleukin 2 receptor (IL-2R) system.
doi:10.2220/biomedres.27.61
pmid:16707844
fatcat:gi2gqdfe4vg4hm5aflxcn5ia3m