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Eukaryotic telomeres have a 12-1 6 nucleotide long deoxyguanosine (dG) rich single-stranded overhang at their molecular termini. Some of the unique features of telomeres are probably attributable to a specialized structure formed by this overhang. In the ciliated protozoan Tetrahymena thermophila, the dG-rich overhang is comprised of approximately two repeats of the sequence d(TTGGGG). Previous work has shown that the synthetic oligonucleotide d(TTGGGG)" can form an unusual non-Watson-Crickdoi:10.1021/bi00455a020 pmid:2337592 fatcat:cilujtfmcfczjoz7iifr47eixm