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Early temporal variation of cerebral metabolites after human stroke. A proton magnetic resonance spectroscopy study
and Purpose: Proton magnetic resonance spectroscopy has documented declines in normal metabolites and long-term elevation of lactate signal after stroke in humans. Within days of stroke, leukocytes infiltrating the infarct zone may produce much of the lactate seen in the subacute and chronic periods. Methods: We examined 10 patients by localized proton magnetic resonance spectroscopy with onedimensional spectroscopic imaging within the first 60 hours after acute nonhemorrhagic cerebraldoi:10.1161/01.str.24.12.1891 pmid:8248973 fatcat:v5tyzy25nrfbhn5vbmclrehzwi