Induction of micronuclei in buccal mucosa on chewing a mixture of betel leaf, areca nut and tobacco

Sudha Sellappa, Mythili Balakrishnan, Sangeetha Raman, Subashini Palanisamy
2009 Journal of Oral Science  
Betel quid containing areca nut and chewing tobacco is used in many parts of India. In this study we evaluated the micronuclei (MN) in buccal mucosa of healthy individuals from southern India, who were regularly chewing a mixture of betel leaf, areca nut and tobacco. A total of 44 subjects were examined. The study population included 15 chewers, 14 chewers with smoking habit and 15 controls with the mean age of 38.57 ± 0.54, 34.50 ± 0.95, and 33.28 ± 0.89 years, respectively. The mean
more » ... of MN was 1.90 ± 1.03 in chewers, 2.00 ± 1.12 in chewers with smoking habits and 0.81 ± 0.66 in controls. There was no significant difference between the mean percentages of the two experimental groups. It can be concluded that a mixture of betel leaf, areca nut, and tobacco is unsafe for oral health. (J Oral Sci 51, [289][290][291][292] 2009)
doi:10.2334/josnusd.51.289 pmid:19550099 fatcat:etlfxf5terdsjmaddknshma3vi