Denosumab-related osteonecrosis of the jaw in a patient with osteoporosis: case report

Zornitsa Mihaylova, Dept. of Oral and maxillofacial surgery, Faculty of Dental medicine, Medical University-Sofia, Evgeniy Aleksiev, Radomir Ugrinov, 1431 Sofia, 1 G. Sofiyski str., Dept. of Oral and maxillofacial surgery, Faculty of Dental medicine, Medical University-Sofia; 1431 Sofia, 1 G. Sofiyski str., Dept. of Oral and maxillofacial surgery, Faculty of Dental medicine, Medical University-Sofia; 1431 Sofia, 1 G. Sofiyski str.
2018 International Journal Of Medical Science And Clinical Invention  
We report a case of osteonecrosis of the jaw (ONJ) associated with denosumab therapy in a 69-year-old female patient being treated for osteoporosis. The patient was admitted in Oral and maxillofacial surgery clinic twice because of nonhealing extraction wounds and inflammatory complications. We recommend conservative therapeutic approach and avoidance of extensive surgery in patients with ONJ.
doi:10.18535/ijmsci/v5i11.03 fatcat:3wnjco7nzfeuvfxmy7evsobsky