Morphokinetics of mesenterial lymphatic node cell populations at exposure of gold nanoparticles in experiment

O.V. Zlobina, Irina O. Bugaeva, Galina N. Maslyakova, S.S. Firsova, Alla B. Bucharskaya, N.G. Khlebtsov, B.N. Khlebtsov, L.A. Dykman
2012 Russian Open Medical Journal  
The influence of gold nanoparticles with different size (1-3 nm, 15 nm and 50 nm) on the morphokinetics of mesenterial lymphatic node cell populations of healthy laboratory animals was investigated. It was established that the oral administration of gold nanoparticles caused the changes of morphokinetics of mesenterial lymphatic node cell populations. The morphological reorganizations in the mesenterial lymphatic nodes testified about activation of migration processes, the proliferation and
more » ... oliferation and differentiation processes of immunocompetent cells, which assumes the presence of immunomodulating action of gold nanoparticles.
doi:10.15275/rusomj.2012.0302 fatcat:hzhnao2uhvfjpf67fu5o54tz4u