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Exercise attenuates inflammation and limits scar thinning after myocardial infarction in mice
American Journal of Physiology. Heart and Circulatory Physiology
Although exercise mediates beneficial effects in patients after myocardial infarction (MI), the underlying mechanisms as well as the question of whether an early start of exercise after MI is safe or even beneficial are incompletely resolved. The present study analyzed the effects of exercise before and reinitiated early after MI on cardiac remodeling and function. Male C57BL/6N mice were housed sedentary or with the opportunity to voluntarily exercise for 6 wk before MI induction (ligation ofdoi:10.1152/ajpheart.00683.2014 pmid:26001415 fatcat:sq7t2ijpzbbm7ilrkvmtirydku