From Muskegon, Michigan

F. W. G.
1889 Journal of the American Medical Association (JAMA)  
showing a livid tint of the skin resembling the tint of asphyxia, and complaining of general weakness, pain near the heart, a soreness beneath the sternum, with a beating pain passing from temple to temple, while to assume the erect position caused giddiness, increasing the cyanotic hue and a stinging pain in the eyes, while to assume the recumbent position gave him freedom from all suffering. Patient had no nausea or vomiting, but body was bathed in perspiration, respiring thirty times per
more » ... te, and a pulse of 110. The medicine was taken about 5 A.M., producing in thirty minutes a form of intoxication and desire to sleep, which our patient indulged in until 10 o'clock. Gave him stimulants and ordered him to keep a recumbent position. I was afterwards informed that he had taken of a mix¬ ture of antifebrin one ounce, and elixir taraxa¬ cum comp. six ounces, of which solution he drank about seventeen drachms. I am sorry to say I did not take his temperature. I take great pleas¬ ure in reporting this case for it certainly demon¬ strates the susceptibility of the patient to this drug. See acknowledges its value, says it is poi¬ sonous, in doses of about 25 grains. Vincberg reports a case of typhoid where 10 grains every four hours produced great cyanosis and a weak compressible pulse of 116. Sexton tells of a case where 10 grains of antifebrin reduced the tem¬ perature from 1050 to 1020 F., 5 grains more were given, which were followed in two hours by cy¬ anosis of the whole body, profuse sweating and collapse; while Pavai Vajna states that in weak patients a dose of 0.25 grams may produce col¬ lapse, while in some cases 1 gram has no effect at all. In conclusion will say the patient-a farmerresumed work the next day.
doi:10.1001/jama.1889.02400800032012 fatcat:cq4m7jrr5vbothyrvd7hfog3zm