Objective: This study aimed to identify the factors affecting depression among individuals living with HIV in Yokohama, Japan. Methods: This study adopted a cross-sectional design. Several self-administered questionnaires were distributed to individuals living with HIV. These questionnaires included the Center for Epidemiologic Studies Depression Scale, the Multidimensional Scale of Perceived Social Support, the Brief Coping Orientation to Problems Experienced Inventory, and a sociodemographic

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... ata form. Results: A total of 100 subjects returned completed questionnaires, with an estimated depression rate of 33% among respondents. In the multivariable logistic regression models, depression was significantly associated with nonregular employment and self-blame coping strategies. Depression was found to be inversely related to social support. Conclusions: This study found that the role of social support is significant among those experiencing depression resulting from living with HIV. Further, along with a better understanding of the coping methods employed by patients in managing such difficulties, effective depression prevention nursing interventions may be evaluated and implemented.