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Role of Extracellular Matrix in Gastrointestinal Cancer-Associated Angiogenesis
International Journal of Molecular Sciences
Gastrointestinal tumors are responsible for more cancer-related fatalities than any other type of tumors, and colorectal and gastric malignancies account for a large part of these diseases. Thus, there is an urgent need to develop new therapeutic approaches to improve the patients' outcome and the tumor microenvironment is a promising arena for the development of such treatments. In fact, the nature of the microenvironment in the different gastrointestinal tracts may significantly influence notdoi:10.3390/ijms21103686 pmid:32456248 fatcat:nz4riwfp2ffxzi5gl5hcipnvnu