Genetic Analysis of 17 Y-STRs in a Mestizo Population from the Central Valley of Mexico

Carla Santana, Gino Noris, Marco Antonio Meraz-Ríos, Jonathan J. Magaña, Emma S. Calderon-Aranda, Maria de Lourdes Muñoz, Rocío Gómez
2014 Human Biology: The Official Publication of the American Association of Anthropological Genetics  
This study aims to portray the complex diversity of the Mexican Mestizo population, which represents 98.8% of the entire population of Mexico. We compiled extended haplotype data of the Y chromosome from populations in the Central Valley of Mexico (CVM), which were compared to other Mestizo and parental (Amerindian, European and African) populations. A complex ancestral relationship was found in the CVM population, suggesting cosmopolitan origins. Nevertheless, the most preeminent lineages
more » ... towards a European ancestry, where the R1b was the most frequent. In addition, important frequencies of Amerindian linages were also found in the Mestizo sample studied. Interestingly, the Amerindian ancestry showed a remarkable substructure, which was represented by the two main founding lineages: QL54 (x M3) and M3. However, even within each lineage a high diversity was found despite the small number of samples bearers of these lineages. Further, we detected important genetic differences between the CVM populations and the Mexican Mestizo populations from the north and south. This result points to the fact that Mestizo populations present different ancestral proportions, which are related to the demographic events that gave origin to each population. Finally, we provide additional forensic statistical parameters that are useful in the interpretation of genetic analysis where autosomal loci are limited. Our findings illustrate the complex genetic background
doi:10.13110/humanbiology.86.4.0289 pmid:25959695 fatcat:ejwvv4vhu5cf7g6qy2x7q4omui