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World Health Organization guidelines recommend that cervical cancer screening programs should prioritize screening coverage in women aged 30 to 49 years. Decisions about target ages and screening frequency depend upon local burden of disease, costs, and capacity. We used cost and test performance data from the START-UP demonstration projects in India, Nicaragua, and Uganda to evaluate the costeffectiveness of screening at various start ages, intervals, and frequencies. We calibrated adoi:10.1016/j.pvr.2015.05.003 fatcat:3upxiyoornarziilyl3zz7g4w4