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On March 12, 2020, WHO has announced COVID-19 as a pandemic due to the uncontrolled spread of SARS-Cov-2 virus, which cause severe acute respiratory tract infections. The virus penetrates the human's body through the droplets of infected person to other person, and binds to certain receptors located on the surface of the human cells. Many challenges appeared when suggesting medicines for the treatment of Covid-19, in addition to several unanswereddoi:10.32388/mask2m fatcat:ryguje6t6jbtxk4gqj4abxgvim