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MgO Implanted in Rat Tibia Bone Marrow is Osteoinductive through the Formation of a Matrix, Containing Hydroxyapatite
Materials Science Forum
Healing of rat tibia after intramedullary implantation of MgO was analysed by Environmental Scanning Electron Microscopy (ESEM) and Energy-Dispersive X-ray spectroscopy (EDX). The results indicated the formation of hydroxyl-apatite (HA) in the entire intramedullary space after 1 week of healing. Then, corroded Mg, MgO and MgCO3 were incubated with DMEM in vitro for 24 h and the surface of the material was analysed by EDX and Time-of-Flight Secondary Ion Mass (ToF-SIMS). The chemical analysis ofdoi:10.4028/www.scientific.net/msf.879.1404 fatcat:s5d3cwpuq5cgpahajczcwh47qy