In Vivo Heteronuclear Magnetic Resonance Spectroscopy [chapter]

Blanca Lizarbe, Antoine Cherix, Rolf Gruetter
2018 Msphere  
Magnetic Resonance Spectroscopy is a technique that has the capability of measuring metabolites in vivo and, in appropriate conditions, to infer its metabolic rates. The success of MRS depends a lot on its sensitivity, which limits the usage of X-nuclei MRS. However, technological developments and refinements in methods have made in vivo heteronuclear MRS possible in humans and in small animals. This chapter provides detailed descriptions of the main procedures needed to perform successful in
more » ... vo heteronuclear MRS experiments, with a particular focus on experimental setup in 13 C MRS experiments in rodents.
doi:10.1007/978-1-4939-7531-0_11 pmid:29341009 fatcat:5ir53yrjp5dkrkjonoxfsxrqv4