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International Journal of Research in Pharmacy and Science Design of Buoyant Famotidine Loaded Microballoons Directed for Upper Small Intestinal Absorption Window
Int. J. Res. Pharm. Sci. 2013 et al. IJRPS
The purpose of this study was to evaluate the potential of floating microballoons. Famotidine was chosen as a model drug because of its poor absorption and short half-life in the lower gastrointestinal tract. A solvent diffusion technique was adopted to prepare famotidine loaded microballoons (FMD-microballoons) using Eudragit S 100 and Hyaluronic acid. The effect of various formulations and process variables including drug content, polymer amount, surfactant concentration, stirring speed andfatcat:spqmskyjdjgllfjg4zvpj7fs2e