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The number of imaging data sets has significantly increased during radiation treatment after introducing a diverse range of advanced techniques into the field of radiation oncology. As a consequence, there have been many studies proposing meaningful applications of imaging data set use. These applications commonly require a method to align the data sets at a reference. Deformable image registration (DIR) is a process which satisfies this requirement by locally registering image data sets into adoi:10.3857/roj.2017.00325 pmid:28712282 pmcid:PMC5518453 fatcat:pyvtjwza25cw7ktfmb6u5wvnlq