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Detecting microsatellites in genome data: variance in definitions and bioinformatic approaches cause systematic bias
2008
Evolutionary Bioinformatics
Microsatellites are currently one of the most commonly used genetic markers. The application of bioinformatic tools has become common practice in the study of these short tandem repeats (STR). However, in silico studies can suffer from study bias. Using a meta-analysis on microsatellite distribution in yeast we show that estimates of numbers of repeats reported by different studies can differ in the order of several magnitudes, even within a single genome. These differences arise because
pmid:19204802
pmcid:PMC2614199
fatcat:lk5p3rz3ozbkpfqxwti6ku37ny