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Objective: We aimed to preliminarily assess whether low-dose aspirin(LDA)is beneficial in preventing preeclampsia in twin pregnancies. Design: An observational cohort study. Setting: Two hospital centers in Chongqing, China. Population: 932 twin-pregnant women. Methods: Among 932 participants, 277 in the First Affiliated Hospital of Chongqing Medical University were routinely treated with aspirin (100mg daily) from 12-16 weeks to 35 weeks of gestational age, while 655 in Chongqing Health Centerdoi:10.22541/au.160278522.21360749/v1 fatcat:7vycvozskfbqhaccic43dkl43i