Sero-epidemiology of Toxoplasma gondii and risk factors among pregnant women in Africa [post]

2019 unpublished
Introduction Infections caused by Toxoplasma gondii is a great public health concern worldwide. Toxoplasma gondii infection in pregnant women may result in abortion, stillbirth, or lifelong disabilities of the fetus. Serologic studies have reported various estimates for seroprevalence of toxoplasmosis among African pregnant women. Estimation of the pooled seroprevalence of this infection is necessary for policy-making and target intervention. Methods We conducted this systematic review and
more » ... analysis according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. A rigorous literature selection was performed by using the databases of PubMed, Google Scholar, and ScienceDirect for the period Jan 1, 2001, to July 31, 2019. Sero-prevalence with 95% CI was presented for each study, and point estimates and their 95% CIs of pooled seroprevalence was then calculated. Findings The search process resulted in the inclusion of a total of 36 studies in the systematic review and meta-analysis. The pooled seroprevalence of Toxoplasma gondii Immunoglobulin G (IgG) in Africa was found to be 46.7% (95%CI: 37.0, 56.4). Geographical-based subgroup analysis showed that the seroprevalence of T. gondii among pregnant women was found to be 65.1% (95% CI: 44.7, 85.5), 50.2% (95%
doi:10.21203/rs.2.18914/v1 fatcat:qnfh635bgnfuvhueih7246jtve