Near-real-time simulations of biolelectric activity in small mammalian hearts using graphical processing units

E.J. Vigmond, P.M. Boyle, L.J. Leon, G. Plank
2009 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society  
Simulations of cardiac bioelectric phenomena remain a significant challenge despite continual advancements in computational machinery. Spanning large temporal and spatial ranges demands millions of nodes to accurately depict geometry, and a comparable number of timesteps to capture dynamics. This study explores a new hardware computing paradigm, the graphics processing unit (GPU), to accelerate cardiac models, and analyzes results in the context of simulating a small mammalian heart in real
more » ... . The ODEs associated with membrane ionic flow were computed on traditional CPU and compared to GPU performance, for one to four parallel processing units. The scalability of solving the PDE responsible for tissue coupling was examined on a cluster using up to 128 cores. Results indicate that the GPU implementation was between 9 and 17 times faster than the CPU implementation and scaled similarly. Solving the PDE was still 160 times slower than real time.
doi:10.1109/iembs.2009.5333738 pmid:19964295 pmcid:PMC3977140 fatcat:fwsexyqr7jez7f4x6kdyahjamu