The goal of this research was to evaluate the quantity and quality of deoxyribonucleic acid (DNA) material collected by at-home-sampling using self-drying buccal swabs in a sterile, laboratory setting compared against a 10,000+ subject sample of real-world swabs processed by consumers and analyzed by a hub-lab of the Sponsor using the same extraction and analysis methodology. Buccal swab DNA concentration was observedon two variables: DNA concentration over time, and DNA sample response to environmental conditions.