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In studies designed to compare different methods of measurement where more than two methods are compared or replicate measurements by each method are available, standard statistical approaches such as computation of limits of agreement are not directly applicable. A model is presented for comparing several methods of measurement in the situation where replicate measurements by each method are available. Measurements are viewed as classified by method, subject and replicate. Models assumingdoi:10.1093/biostatistics/kxg043 pmid:15208202 fatcat:bxlp6vej3rb2vbrzginawr2jja