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Angiotensin II receptor blockers (ARBs), or sartans, are a group of pharmaceuticals that modulate the renin-angiotensin-aldosterone system (RAAS). They are more successful in blocking the effects of AT II compared to ACE inhibitors, and are characterized by higher tolerability. Large comparative studies with ARA II were completed lately, including studies on long-term efficacy and impact on prognosis. The obtained evidence base contributed to the expansion of indications for clinical use ofdoi:10.21518/2079-701x-2014-17-66-71 doaj:7992255a4e614fdb871375935f514d9b fatcat:32m7fjt7bfaf5o6ihilcwsuiwi