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Due to the nature of involved optics, the depth of field in imaging systems is usually constricted in the field of view. As a result, we get the image with only parts of the scene in focus. To extend the depth of field, fusing the images at different focus levels is a promising approach. This paper proposes a novel multifocus image fusion approach based on clarity enhanced image segmentation and regional sparse representation. On the one hand, using clarity enhanced image that contains bothdoi:10.1364/oe.21.005182 pmid:23482052 fatcat:vmmpts2exbfwtle3ewz7se3vi4