Brief about Basic Medical Sciences e-Conference 2021 ( BMS e-CON-2021)
Journal of Clinical and Diagnostic Research
The conference had 890 confirmed registrations which includes the delegates from states all over India and a few foreign countries. There were 137 papers for oral and 29 for Young Research Scholar Award presentations in Faculty, PhD, Postgraduate and Undergraduate categories. E-posters competition was also held for undergraduates. There were 14 eminent national and international speakers who made the conference a scientific feast by sharing their experiences and knowledge on various topics
... ining to the theme of the conference. The theme of the conference: "Exploring the Newer Modalities in Teaching -Learning and Research in Basic Medical Sciences during COVID-19 Era" was chosen because of the unprecedented situation that arouse after the outbreak of COVID-19 leading to digitalisation of most of the events related to education like teaching, learning and to some extent research. COVID-19 pandemic has made everyone feel the need to adopt the online teaching-learning methodology to serve the dual purposes of continuation of education while discontinuation of the chain of transmission of the virus to a number of people. Basic research in molecular biology, immunology and cell biology provides an infinite amount of data and knowledge. Applied research uses that information to understand the pathophysiology of diseases of patients. Research demands critical thinking, logical reasoning and creative application by exploring newer approaches, techniques and methods. So, the health professionals should be aware of the latest research advances. The next generation professionals should be aware of the latest research advances and have to be assertive in their practices which should be evidence based for efficient and effective patient care. Focus of this conference was on: Exploring newer modalities in teaching -learning and research in basic medical sciences during COVID-19 era with special emphasis on: 1. Newer technology in teaching and learning and experience sharing. 2. Research Ethics and challenges during COVID-19 Era. 3. Development of vaccines and diagnostic kits using newer molecular based technologies. 4. Myths and facts related to COVID-19 5. Laboratory Medicine in MBBS curriculum Brief about Basic Medical Sciences e-Conference 2021 (BMS e-CON-2021) Introduction: Islet of Langerhans, the endocrine pancreas plays a significant role in glucose metabolism. Obesity and insulin resistance are the major factors responsible for beta-cell dysfunction. Whereas Asian Indian population has increased susceptibility to diabetes despite having lower BMI. The morphology of islets plays a significant role in beta-cell function. Aims: To study the regional variation and microarchitecture of the islets including beta-cell proportion in the pancreas of non-diabetic Indian population. Materials and Methods: Authors observed islet morphology and beta-cell area proportion by Large-scale computer-assisted analysis in 20 adult human pancreases in the non-diabetic Indian population. Immunohistochemical staining with anti-synaptophysin and anti-insulin antibodies were used to detect islet and beta cells, respectively. Whole slide images were analysed using ImageJ software. Results: Endocrine proportions were heterogeneously increasing from head to tail with maximum distribution in the tail region. Even though larger islets were predominately confined to the tail region, which is 30 to 45 % less than the American population. The islets in the Indian population were relatively smaller in size, but they have more beta cells (20%) when compared to the American population. Conclusion: The beta cells of larger islets are functionally more active than the smaller islets via the paracrine effect. Despite having more beta cells in Indians, there are functionally less active in smaller islets. Thus, a reduction in the number of larger islets may be one of the probable reasons for the increased susceptibility of Indians to diabetes even at lower BMI.