Ontogeny of the long form of leptin receptor gene expression in the porcine ovarian follicles

N. Smolinska, T. Kaminski, G. Siawrys, J. Przala
2013 Polish journal of veterinary sciences  
Leptin is a polypeptide hormone produced predominantly in adipocytes. It has been found to be implicated in the regulation of satiety and energy homeostasis. A role for leptin in reproduction was later suggested by findings that this hormone may be involved in the regulation of the hypothalamic- pituitary-gonadal axis via endocrine, paracrine and/or autocrine pathways. The objective of the study was to investigate the ontogeny of the long isoform of leptin receptor (OB-Rb) gene in porcine
more » ... n follicles. The expression of OB-Rb gene was detected in porcine primordial, primary, secondary and antral follicles by in situ hybridization. In summary, our data suggest that leptin might have a direct effect on porcine follicles and plays an important role in the follicular development.
doi:10.2478/pjvs-2013-0014 pmid:23691582 fatcat:byd7oledrvfdvo54jd3vi4dk2m