ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

Gabriela Bindea, Bernhard Mlecnik, Hubert Hackl, Pornpimol Charoentong, Marie Tosolini, Amos Kirilovsky, Wolf-Herman Fridman, Franck Pagès, Zlatko Trajanoski, Jérôme Galon
2009 Computer applications in the biosciences : CABIOS  
We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO
more » ... ovides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.
doi:10.1093/bioinformatics/btp101 pmid:19237447 pmcid:PMC2666812 fatcat:6q3lnfp7fbgk5dkuj5h2tn7tim