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The diagnosis of tuberculosis is elusive because of its insidious nature and distinct clinical presentations. Isolated hepatic tuberculosis is a rare clinical entity among patients with tuberculosis. A 45 years old man was presented with complaints of upper abdominal pain, nausea and vomiting. Proteinuria induced by amyloidosis secondary to isolated hepatic tuberculosis was detected in routine urinalysis. Hepatic tuberculosis diagnosis was established by positive tuberculosis polymerase chaindoi:10.14740/jmc2140w fatcat:pl3jfceyrjbp7jot3n2dpew43e