Adolescents and young adults with cancer have special characteristics and needs. Aims: This study highlighted psychosocial challenges, fertility issues and secondary diseases encountered in adolescents and young adults with cancer. This work is meant to be a platform for future interventions for cancer in this demographic. Methods: We investigated the latest edition of the Jordan Cancer Registry (JCR) and our more comprehensive institutional database during 2000-2012. Smoking, obesity and

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... ity preservation were addressed briefly as important issues among AYA patients. Results: Cancer among adolescents and young adults represents 16.3% of all new cancer cases and has increased by 25% over the past 12 years. Women are more likely to be involved (female: male ratio of 1.44: 1) because of thyroid and breast cancers. Five-year survival rate for the AYA group was 72.4%, which was significantly better than for adults aged ≥ 40 years (59.8%) but worse than for paediatric patients aged Conclusions: Cancer in adolescents and young adults represents a substantial and growing 1 / 16 WHO EMRO | Cancer care for adolescents and young adults in Jordan proportion of oncological diagnoses. Due to their special needs and treatment complications, a dedicated service is urgently needed.