Thrombin-promoted release of UDP-glucose from human astrocytoma cells: Thrombin-promoted release of UDP-glucose

L. Seminario-Vidal, S. M. Kreda, E. R. Lazarowski, C. Van Heusden
The P2Y14 receptor is activated by UDP-sugars, most potently by UDP-glucose, but not by free nucleotides, suggesting that UDP-glucose is the cognate agonist for this receptor. However, evidence for regulated release of UDP-glucose is scarce. In the present study, the occurrence of receptor-promoted release of UDP-glucose was investigated, using 1321N1 human astrocytoma cells.
doi:10.17615/afh8-3z02 fatcat:q644767b6nf45f3pfuwoqdjhqy