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The appearance of immune checkpoint inhibitors has been a major turning point in cancer therapy. The success of immune checkpoint therapy has revolutionized theˆeld of cancer therapy, and immunotherapy has joined the cancer treatment ranks as a pillar. To induce eŠective anti-tumor immune responses, it is necessary both to enhance the activity of immune cells and to block immune suppression by tumor cells. Carrier type drug delivery systems based on nanobiotechnology (nano DDS) represent adoi:10.1248/yakushi.18-00162 fatcat:cqomubd4ezafrmxlj2pbpsjdzu