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The T cell antigen receptor (TCR) consists of an ␣␤ heterodimer and associated invariant CD3␥, ␦, ⑀, and chains (TCR/CD3 complex). The general stoichiometry of the receptor complex, which is believed to be one molecule each of TCR␣, TCR␤, CD3␥, and CD3␦ and two molecules each of CD3⑀ and CD3, is not clearly understood. Although it has been shown that there are two chains of CD3⑀ and CD3, the stoichiometry of CD3␥ or CD3␦ chains in the surface antigen receptor complex has not been determined. Indoi:10.1074/jbc.m406145200 pmid:15459203 fatcat:6beozjkrwnbg3i3uegwbyzm7zm