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Executive functions depend on the ability to represent relations between objects and events, and the prefrontal cortex provides the neural substrate for this capacity. Patients with probable Alzheimer's disease (AD) and control participants were administered measures of working memory and reasoning that varied systematically in their relational complexity. AD patients showed impairment on reasoning measures that required the online integration of relations but performed as well as controldoi:10.1037/0894-418.104.22.1686 pmid:15099152 fatcat:utuyfh4twbadllv44dbtwbkr5a