Today, ethics has become an integral part of human life and moral behavior plays an important role in improving the performance and effectiveness of organizations. As a result, this study aimed to determine the role of emotional and cognitive empathy, moral metacognition and quality of life in predicting moral behavior nurses. Method: The present study was cross-sectional from type of correlation. The study population includes nurses the hospitals of Varamin city in 2019 (N=359) which from them

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... 200 nurses were selected as a sample by stratified random sampling method. Data were collected by the questionnaires of emotional and cognitive empathy (Reniers et al), moral metacognition (McMahon & Good), quality of life (WHO) and moral behavior (Swanson & Hill). Data were analyzed by Pearson correlation coefficient and multiple regression with enter model methods in SPSS-19 software. Results: The findings showed that emotional empathy, cognitive empathy, moral metacognition and quality of life had a positive and significant relationship with moral behavior of nurses. In addition, the variables of emotional and cognitive empathy, moral metacognition and quality of life were able to predict 56% of the changes in moral behavior of nurses (P<0.01). Conclusion: According to the results, to improve the moral behavior of nurses, their emotional and cognitive empathy, moral metacognition and quality of life can be improved.