Abstracts for the 29th Annual Meeting of the Japan Neuroscience Society (Neuroscience2006)

2006 Neuroscience research  
Psychophysicists and sensory physiologists emphasize the effects of sensory stimuli on decision-making. Psychologists and economists, however, have long known that decision-making is influenced substantially by an organism's prior experience concerning the "value" of alternative choices, expressed in terms of likely positive or aversive consequences. Brain circuitry that mediates decision-making should reflect both sensory and value influences, and we have recently been able to demonstrate such
more » ... effects at the behavioral and neurophysiological levels. To measure "value", we have developed a probability matching paradigm for monkeys in which the animal's valuation is revealed through the proportion of choices allocated to alternative behaviors. In neurophysiological recordings, we have found that neurons in the lateral intraparietal area (LIP) code value, although LIP is unlikely to be the site where value is originally computed. Our results suggest that signals from multiple sources within the brain, including representations of sensory stimuli as well as value converge in areas such as LIP to render behavioral decisions.
doi:10.1016/j.neures.2006.04.004 fatcat:mja5yvu2tbcjrmfx3a7abvvicm