Legionella pneumophila lipopolysaccharide activates the classical complement pathway

C S Mintz, D R Schultz, P I Arnold, W Johnson
1992 Infection and Immunity  
Legionella pneumophila is a gram-negative bacterium capable of entering and growing in alveolar macrophages and monocytes. Complement and complement receptors are important in the uptake of L. pneumophila by human mononuclear phagocytes. The surface molecules of L. pneumophila that activate the complement system are unknown. To identify these factors, we investigated the effects of L. pneumophila
doi:10.1128/iai.60.7.2769-2776.1992 fatcat:msjzk45tsbapzicyxgb6n3j42e