The purpose of this study was prediction of psychological well-being based on hope and perceived social support among women-headed households. The research method was descriptive and correlative. The statistical population consisted of all women-headed households that are under support of the Imam Khomeini Relief Foundation Songhor city. From among them, 150 women were selected with available sampling. Participants completed the Psychological Well-Being Scale (Ryff, 1995); Adult Hope Scale

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... eider, 1991) and Multidimensional Scale of Perceived Social Support (Zimet et al, 1988). For the analysis of the data, Pearson correlation and multiple regressions were used. The results showed that there is a positive and significant relationship between hope and psychological well-being (R= 0.531, P <0.01). Also, there is a positive and significant relationship between perceived social support and psychological well-being (R= 0.751, P<0.01). Regression analysis showed that hope and perceived social support, predict %60 of psychological well-being variance. Based on the findings, it can be concluded that hope and perceived social support are important factors in prediction of psychological well-being. Therefore, it is suggested that these factors be seriously considered preventive and therapeutic interventions.