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Safety, efficacy and efficiency of neurosurgical robots are defined by their design (i.e., framed and non-framed) and procedural workflow (from image to surgery). The present study describes the quality indicators of three different robots in brain and spine surgery. This single-center study enrolled 252 patients over a ten-years period. Safety (complication rate) and efficacy (diagnostic yield, pedicle screw placement) were determined. Predictors of workflow efficiency (e.g., skin-to-skin)doi:10.1002/rcs.2282 pmid:34030218 fatcat:ngopav2xibagxlkan26lmhc7bq