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Cigarette smoke extract stimulates bronchial epithelial cells to undergo a SUMOylation turnover
2020
BMC Pulmonary Medicine
Background Chronic obstructive pulmonary disease (COPD) characterized by the airway and lung inflammation, is a leading cause of morbidity and mortality worldwide, especially among smokers over 40 years of age and individuals exposed to biomass smoke. Although the detailed mechanisms of this disease remain elusive, there is feasible evidence that protein posttranslational modifications (PTMs) may play a role in its pathoetiology. We thus conducted studies to dissect the effect of cigarette
doi:10.1186/s12890-020-01300-w
pmid:33097022
pmcid:PMC7584069
fatcat:widelnv7kbbujlc6p4ftfpjjbu